Trials & Filings

Valneva’s Inactivated, Adjuvanted COVID-19 Vax Achieves Positive Data

VLA2001 was highly immunogenic with more than 90% of study participants developing significant levels of antibodies to SARS-CoV-2 virus spike protein.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Valneva SE achieved positive data for Part A of the Phase 1/2 clinical trial of its inactivated, adjuvanted COVID-19 vaccine candidate, VLA2001. Based on this data, the company plans to begin a Phase 3 clinical trial by the end of April 2021, subject to regulatory approval. In study VLA2001-201, three dose levels of VLA2001 (low, medium, high), based on a schedule of two doses with vaccinations three weeks apart, were evaluated in 153 healthy adults aged 18 to 55 years. VLA2001 was general...

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